منابع مشابه
Recycling the Cell Cycle Cyclins Revisited
I discuss advances in the cell cycle in the 21 years since cyclin was discovered. The surprising redundancy amongst the classical cyclins (A, B, and E) and cyclin-dependent kinases (Cdk1 and Cdk2) show that the important differences between these proteins are when and where they are expressed rather than the proteins they phosphorylate. Although the broad principles of the cell cycle oscillator...
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Proactive An agent achieves goals, implicit or explicit. Its behaviour is teleological, planned and future-oriented. Reactive An agent perceives and reacts to environmental change. Its behaviour is causal and past-determined. Model-based It uses models of the world to guide its perception and behaviour. Learning-oriented It acquires new behaviours and new models. Rational It reasons, solves pro...
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The strange sets which arise in deterministic low-dimensional dynamical systems are analysed in terms of (unstable) cycles and their eigenvalues. The general formalism of cycle expansions is introduced and its convergence discussed. PACS numbers: 0320,0545
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Phosphorus sets the pace of marine biological productivity on geological time scales. Recent estimates of Precambrian phosphorus levels suggest a severe deficit of this macronutrient, with the depletion attributed to scavenging by iron minerals. We propose that the size of the marine phosphorus reservoir was instead constrained by muted liberation of phosphorus during the remineralization of bi...
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Cancer is characterized by abnormally excessive cell proliferation. Cell proliferation, the process by which a cell grows and divides to produce two daughter cells. Each of these daughter cells divides to produce two new cells, steps that are called cell cycle. Meanwhile, apoptosis is a highly regulated process of cell death, which is involved not only in the development of shape and morphogene...
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ژورنال
عنوان ژورنال: Cell
سال: 2004
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(03)01080-8